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Aspirate from an abdominal mass of a 5-year-old spayed female Shetland Sheepdog. The presenting complaint was anorexia and vomiting for 1.5 weeks. An abdominal radiograph suggested a possible mid-abdominal mass. On ultrasound, a mixed echogenicity liver mass and an extremely large mixed echogenicity abdominal mass...

An 11-year-old spayed female Boston Terrier had a mass removed two months ago, but it was not submitted for histopathologic evaluation. Just caudal to the scar from the previous surgery, a large soft mass is now present, which is possibly the inguinal lymph node. Many...

Aspirate from the spleen of a 9-year-old female Miniature Schnauzer. The presenting complaint was intermittent hematochezia. Laboratory findings revealed anemia, thrombocytopenia, hypoalbuminemia, and hyperglobulinemia. The spleen was aspirated and submitted for evaluation. This image of the splenic aspirate consists of few small, mature lymphocytes, one erythroid...

Aspirate from the spleen of a 9-year-old neutered male Labrador. On ultrasound, the spleen appeared heterogeneous with focal hypoechoic nodules. Laboratory findings revealed a mild anemia, mildly increased liver enzymes, and a serum globulin concentration >7 g/dL. The spleen was aspirated and submitted for evaluation. This...

Aspirate of a right foreleg soft tissue mass of a 6-year-old female Tibetan Spaniel. The mass has been growing slowly over the last few months. The image consists of numerous spindle to stellate shaped cells with indistinct cytoplasmic borders that exhibit a veiling appearance. The cytoplasm...

The image consists of several large spindle to irregularly-shaped cells (osteoblasts) with an abundant amount of lightly to moderately basophilic cytoplasm that, contains many fine pink granules. The nucleus is large, round to oval, and commonly eccentric replaced, with coarsely stippled chromatin and 1-2 visible...

The image consists of several clusters of polygonal epithelial cells with a small amount of lightly basophilic cytoplasm and a large round to oval nucleus with coarsely stippled chromatin. Anisokaryosis is moderate. The diagnosis is carcinoma, suspect pulmonary carcinoma, but a metastatic carcinoma cannot be...

The image consists of many large immature lymphocytes with large prominent nucleoli. Many lymphoglandular bodies (cytoplasmic fragments) and many free nuclei are also present. The diagnosis is high-grade lymphoma. ...

The image consists of several mast cells, numerous eosinophils and few spindle shaped cells (fibrocytes). The mast cells are moderately to well granulated and have round to oval nucleus with finely stippled chromatin. Anisokaryosis and anisocytosis are mild. The diagnosis of mast cell tumor. Biopsy/histopathology...

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